geographic atrophy icd 10. Optic atrophy assoc with retinal dystrophy; Optic atrophy associated with retinal dystrophy; Postinflammatory optic atrophy. geographic atrophy icd 10

 
 Optic atrophy assoc with retinal dystrophy; Optic atrophy associated with retinal dystrophy; Postinflammatory optic atrophygeographic atrophy icd 10  Age-related macular degeneration (AMD) is the main cause of blindness in the developed world in subjects aged ≥55 years, mainly with risk factors and genetic predisposition, with the number of patients affected being counted in millions and likely to increase with the population longevity

eating a diet low in fruits and vegetables. 2B1 - other international versions of ICD-10 H44. 30 may differ. doi: 10. Last updated: September 2023. 15 is an approximate match for comparison and conversion purposes. 89 became effective on October 1, 2023. These lesions typically appear. This is the American ICD-10-CM version of H35. The retinal pigment epithelium (RPE), choriocapillaris and neurosensory. Objectives: The objective of our study was to review the current knowledge on Age- Related Macular Degeneration, including pathogenesis, ocular manifestations, diagnosis and ancillary testing. 50 became effective on October 1, 2023. 1016/j. Chorioretinal atrophy (CR) is the result of loss of the choriocapillaris, Retinal Pigment Epithelium (RPE), and the outer layers of the sensory retina. The 2024 edition of ICD-10-CM H44. Cancer of the of tongue; Cancer of the tongue, squamous cell; Primary malignant neoplasm of tongue; Squamous cell carcinoma of tongue. 89 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. 89 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. Apellis Pharmaceuticals. J2781, effective October 1, 2023. The ICD-10-CM diagnosis codes required for billing are: H35. Geographic atrophy (GA) is a chronic eye condition in which the cells in the retina slowly break down and die. cdc. 52 : H00-H59. Applicable To. Short description: Muscle wasting and atrophy, NEC, left forearm The 2024 edition of ICD-10-CM M62. This new treatment won’t reverse vision loss but may slow the growth of GA lesions by 18% to 22% in the first 12 months. H47. 52 contain annotation back-references that may be applicable to H44. Introduction. 0 became effective on October 1, 2023. Purpose : Geographic atrophy (GA) represents an important concern as it leads to visual impairment and affects more than 5 million age-related macular degeneration (AMD) patients worldwide. This condition greatly impairs your central vision. 1. Introduction. Showing 1-25: ICD-10-CM Diagnosis Code K14. 523 for Atrophy of globe, bilateral is a medical classification as listed by WHO under the range - Diseases of the eye and adnexa . 4. 091 - other international versions of ICD-10 H31. 30 is applicable to adult patients aged 15 through 124 years. . 884 MGD, left upper lid. GA is distinct from wet or neovascular AMD (nAMD),. 32. 1 became effective on October 1, 2023. Convert H35. Primary optic atrophy, bilateral. 529 became effective on. 81% of the population of the United States has geographic atrophy in at least one eye, affecting 3. 2024 ICD-10-CM Range H00-H59. S. The atrophy is called geographic because confluent loss of the. This may be due to loss of circulation from the choriocapillaris or from an inflammatory event. This is the American ICD-10-CM version of G31. 521 for Atrophy of globe, right eye is a medical classification as listed by WHO under the range - Diseases of the eye and adnexa . 291–Other optic atrophy, right eye H47. This is the American ICD-10-CM version of H44. It is found in the 2022 version of the ICD-10 Clinical Modification (CM) and can be used in all HIPAA-covered transactions from Oct 01, 2021 - Sep 30, 2022 . ↓ See below for any exclusions, inclusions or special. 1 [convert to ICD-9-CM] Atrophy of kidney (terminal) Atrophy of kidney; Renal atrophy; Unilateral renal atrophy. The 2024 edition of ICD-10-CM H31. (ICD-11) (eMethods 2 in the Supplement). A disorder of the central nervous system characterized by gradual and progressive loss of neural tissue and neurologic function. 4. This was the first year ICD-10-CM was implemented into the HIPAA code set. ICD-10 codes covered if selection criteria are met: H35. 89 is applicable to adult patients aged 15 - 124 years inclusive. It is always the provider’s responsibility to determine the appropriate clinical diagnosis, and to submit true and correct claims for services rendered. Geographic atrophy (GA) of the retinal pigment epithelium (RPE) is a devastating complication of age-related macular degeneration (AMD). The 2024 edition of ICD-10-CM H47. Other optic atrophy, right eye. International. 79 may differ. 293 became effective on October 1, 2023. Drusen-related GA remains a large public health concern due to the. 30 is a billable diagnosis code used to specify a medical diagnosis of unspecified macular degeneration. Atrophy of left orbit. 1. 4 may differ. This is the American ICD-10-CM version of H47. Showing 1-25: ICD-10-CM Diagnosis Code H47. Geographic atrophy (GA) affects 5 million individuals worldwide and is an advanced stage of dry age-related macular degeneration (AMD), leading to vision loss and accounting for 20% of legal blindness cases in North America. 529 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. 8 may differ. 4, 5 Although neovascular AMD (nAMD) can be successfully treated with VEGF inhibitors, the treatment of GA remains a substantially unmet need. injury (trauma) of eye and orbit ( S05. This is the American ICD-10-CM version of H47. The 2024 edition of ICD-10-CM H44. Pars plana cysts are clear, bullous balloon-like structures that extend from the non-pigmented ciliary epithelium of the pars plana to the peripheral retina under the vitreous cortex (Figure 4). The 2024 edition of ICD-10-CM L91. A Yes. FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. M62. When using code H35. The U. Other optic atrophy, unspecified eye. S. In age-related macular degeneration (AMD), the development of geographic atrophy (GA) differs partially but fundamentally from its subsequent expansion: in its time-course, its risk factors, and its underlying mechanisms. 532 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. Déjérine-Sottas disease. Learn more about ICD-10 codes in the ICD-10-CM for Ophthalmology. This is the American ICD-10-CM version of H44. 011. Search All ICD-10 Toggle Dropdown. Understanding the progression to geographic atrophy (GA) in late dry age-related macular degeneration (dAMD) can support development opportunities for dAMD treatments. RPE cells are “one of the most metabolically active tissues in the human body,” he says, and are responsible for cleaning out the many waste products that develop in the retina. [convert to ICD-9-CM]G32. 211 may differ. Keenan. 532 became effective on October 1, 2023. Advanced age-related macular degeneration (AMD) is defined by the presence of geographic atrophy (GA) or choroidal neovascularization. The 2024 edition of ICD-10-CM H35. 459 may differ. K14. 459 became effective on October 1, 2023. We highlight clinical trial data from phase I, II, and III studies. There are 130 terms under the parent term 'Atrophy' in the ICD-10-CM Alphabetical Index . Introduction Geographic atrophy (GA) is considered the late stage of the dry form of age-related macular degeneration (AMD)(1). 1,2. ophtha. On the pages of a book, it may seem like certain letters are missing when you look straight at the page. J. CMS Long Descriptor2. 351. Outer retinal tubulation (ORT) is a feature of photoreceptor rearrangement after retinal injury. 89 to ICD-9-CM. Dry age-related macular. Injection, pegcetacoplan, intravitreal, 1 mg*. With. 521 may differ. Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes. The 2024 edition of ICD-10-CM G31. This is the American ICD-10-CM version of H44. H47. Code History. 3114 became effective on October 1, 2023. If two injections are performed the same day — one treatment for geographic atrophy and a second with an anti-VEGF — due to the MUE, only one injection can be paid. The Food and Drug Administration (FDA) has accepted for Priority Review the New Drug Application (NDA) for pegcetacoplan for the treatment of geographic atrophy (GA). Numerator Options: Introduction Understanding the progression to geographic atrophy (GA) in late dry age-related macular degeneration (dAMD) can support development opportunities for dAMD treatments. 70. 319 may differ. The information provided is subject to change without notice and should be verified by the provider for each patient. G00-G09 Inflammatory diseases of the central ner. high cholesterol. -) 124 Other disorders of the eye with mcc or thrombolytic agent. Optic atrophy assoc with retinal dystrophy; Optic atrophy associated with retinal dystrophy; Postinflammatory optic atrophy. The patients by now, because the foveal became involved, are starting to use their eccentric fixation with a. ICD-10 code H47. 2. 522 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. Geographic Atrophy (GA) is an advanced form of dry macular degeneration in which large, well-demarcated sections of the retina stop functioning. The code H35. The 2024 edition of ICD-10-CM H31. 4 Accurate documentation of GA is important for patients in clinical trials and for new therapies as. 212 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. high blood pressure (hypertension) obesity. 351 became effective on October 1, 2023. Geographic atrophy (GA) is generally defined as the advanced or late stage of dry age-related macular degeneration (AMD) with a circular area of atrophy of 175 μm or more. Summary. Your symptoms will correspond with where you are in the geographic atrophy disease process. This is the American ICD-10-CM version of H35. 5; ICD-11: 9B70; OMIM: 153700; UMLS. 22 - Hereditary optic atrophy. The Food and Drug Administration (FDA) has approved Syfovre ™ (pegcetacoplan injection, for intravitreal use) for the treatment of geographic atrophy (GA) secondary to age. 81 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. Epub 2018 Oct 8. 31 - other international versions of ICD-10 H35. 40 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. Fact Checked. The 2024 edition of ICD-10-CM H35. 89 is a billable diagnosis code used to specify other specified retinal disorders. Diseases of the eye and adnexa. 40 may differ. ICD-10-CM Code for Atrophy of globe H44. K14. Purpose of review: This review describes therapeutic research programs for geographic atrophy (GA) due to age-related macular degeneration (AMD). DescriptionThis is the official approximate match mapping between ICD9 and ICD10, as provided by the General Equivalency mapping crosswalk. ICD-9. 49 to ICD-9-CM. The last stage of dry AMD is called geographic atrophy. 351 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. Although patients with AMD may benefit from supplements consisting. Visual changes can often be detected with an Amsler grid Visual field testing . . Atrophy of scrotum, seminal vesicle, spermatic cord, tunica vaginalis and vas deferens; Chylocele, tunica vaginalis (nonfilarial) NOS;. Aetna will not provide coverage for the treatment of geographic atrophy (GA) secondary to a condition other than AMD (such as Stargardt disease, cone rod dystrophy, toxic maculopathies). Geographic atrophy (GA) is considered the late stage of the dry form of age-related macular degeneration (AMD) (1). Purpose: Late-onset central areolar choroidal dystrophy (CACD) may easily be confused with geographic atrophy (GA) in AMD. In the current therapeutic landscape, intravitreal anti-vascular endothelial growth factor (anti-VEGF) therapies have been central to the management of neovascular AMD (also known as wet AMD), whereas treatments for geographic atrophy have lagged behind. Geographic atrophy in age-related macular degeneration and TLR3. org Learn how to use the ICD-10 codes for dry AMD (H35. Purpose To examine the association between geographic atrophy (GA) disease characteristics and mortality risk. doi: 10. ICD-10-CM Diagnosis Code H05. Geographic atrophy in dry AMD is determined clinically by a distinct, sharply circumscribed area of depigmentation or apparent RPE atrophy through which choroidal vessels can be seen. A type 2 excludes note indicates that the condition excluded is not part of the condition it is excluded from but a patient may have both conditions at the same time. The 2024 edition of ICD-10-CM H47. Fluorescein. G10 Huntington's disease. 1 GA appears as lesions which are the result of dead retinal pigment epithelium (RPE) and photoreceptor cells with closure of the underlying. Official Long Descriptor. Nonexudative AMD Nonexudative (dry or atrophic) AMD accounts for 90 percent of allVersions 10, 11 Beta Draft, 10 Clinical Modification, and Proposed 11 ICD-1017 and ICD-10-CM (2016)18 ICD-11 Beta Draft21 ICD-10-CM (2017)19,20 and Proposed ICD-11 Current international version of ICD by the WHO Former (FY2016) US version of the ICD-10-CM by the CDC Draft international version of ICD-11 by the WHO; revisions still in progressICD-10-CM; H35. CORCORAN, COE. In March 2016, the Centers for Disease Control released proposed ICD-10 changes for October 1, 2016. Significant atrophy of the retinal pigment epithelium (RPE) was frequently apparent beneath. Added HCPCS J2781. 211 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. H47. 119 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. Approximately 10-15% of the cases of macular degeneration are the “wet” (exudative) type. Food and Drug Administration (FDA) has approved SYFOVRE™ (pegcetacoplan injection) for the treatment of geographic atrophy (GA) secondary to. The 2024 edition of ICD-10-CM H35. This is the American ICD-10-CM version of H47. Apellis Pharmaceuticals reported topline results from two phase 3 studies investigating pegcetacoplan in patients with geographic atrophy secondary to age-related macular degeneration, according. gov/nc hs/icd/ic d10cm. This was the first year ICD-10-CM was implemented into the HIPAA code set. This is the American ICD-10-CM version of H31. This is the American ICD-10-CM version of K13. Sudden-onset of blurring or distortion of vision is often the presenting symptom in the neovascular form. Contents. 0 became effective on October 1, 2023. H44. Significant atrophy of the retinal pigment epithelium (RPE) was frequently apparent beneath. Added ICD-10-CM H35. The equivalent ICD-10 diagnoses associated with these GA and pre-GA lesions are: “nonexudative AMD, intermediate dry stage” for high-risk drusen, iRORA, and. Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD), characterized by atrophic lesions that first start in the outer retina and progressively expand to cover the macula and the fovea, the center of the macula, leading to irreversible loss of vision over time. Geographic atrophy (GA) is a debilitating eye disease affecting 5 million individuals globally with expected growth to reach approximately 9 to 10 million individuals by the year 2040. 9 became effective on October 1, 2023. 89 - other international versions of ICD-10 K31. 41 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail. 292 may differ. GA is a leading cause of blindness, impacting more than 1 million individuals in the United States and 5 million individuals worldwide. 291 may differ. With. H47. 81 became effective on October 1, 2023. Applicable To. The 2024 edition of ICD-10-CM H47. However, in addition to providing granular severity and laterality information for geographic atrophy, ICD-10 codes were used in this study based on existing. This causes an abnormal appearance of the optic nerve and changes the color of the tissue surrounding the optic nerve. 212 may differ. 88B MGD, left upper and lower lids. See GA Differently. A disorder characterized by the degeneration and thinning of the epidermis and dermis. Izervay slowed progression of geographic atrophy effectively and quickly in clinical trials. Although there is currently no approved treatment for GA, improved understanding of AMD mechanisms and risk factors has. Geographic atrophy (GA) is a progressive, advanced form of age-related macular degeneration (AMD), and is characterized by irreversible atrophy of the retinal pigment epithelium photoreceptors and choriocapillaris, 1, 2 and is therefore associated with significant, irreversible loss of vision. K14. Age-related macular degeneration (AMD) is a multifactorial disease and a leading cause of vision impairment in elderly people in Western society. Conclusions: Age-related. GA is distinct from wet or neovascular AMD (nAMD), the other form of advanced AMD. This results in poor retinal function and vision loss. The start date was selected based on the availability of the ICD-10 code for GA, confirming disease severity and eye laterality. Synonyms: left globe atrophy, phthisis bulbi , phthisis bulbi of left eye. The primary endpoint for both trials was the mean rate of change in geographic atrophy, as. 292 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. Chapter 7 - Diseases of the eye and adnexa (H00-H59) » Disorders of optic nerve and visual pathways (H46-H47) » Optic atrophy (H47. ICD-10-CM Diagnosis Code D31. The 2024 edition of ICD-10-CM H31. The 2024 edition of ICD-10-CM H35. 30 is applicable to adult patients aged 15 through 124 years. 2. 101 - H31. --Vision usually recovers within 2 mo. Introduction. Geographic tongue, also known by several other terms, is a condition of the mucous membrane of the tongue, usually on the dorsal surface. 313 ICD-10 code H35. To evaluate macular atrophy (MA) presence in the 24-month HARBOR study ( NCT00891735) for neovascular age-related macular degeneration (AMD). How to use the ICD-10 codes for age-related macular degeneration. Gualino V, Tadayoni R, Cohen SY, et al. The application for the first potential drug indicated for treatment of GA was submitted by Apellis Pharmaceuticals,. Basal laminar drusen/Cuticular drusen is an uncommon entity. 093 became effective on October 1, 2023. Geographic atrophy is defined by the irreversible loss of retinal structures, including photoreceptor cells, retinal pigment epithelium, and choriocapillaris. 522 is a billable diagnosis code used to specify atrophy of globe, left eye. 3 GA is estimated to affect ~5. 522 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. Systematic review methodology: Relevant publications on Age-Related Macular Degeneration that were published until 2014. 1 AMD is the leading cause of permanent vision loss in people over the age of 65 in developed countries, 2 and the risk of developing AMD increases with age. Use Additional. Muscle wasting and atrophy, not elsewhere classified, back, lumbosacral. 0) atrophy of edentulous alveolar ridge (K08. Introduction. Availabl e at: w. ICD-9-CM 362. L. 7-9% of patients never experience vision loss, but have an aberrant EOG with normal ERG. Geographic atrophy can affect one or both eyes, and a patient with the disease in one eye is more likely to develop it in the other. H35. This is the American ICD-10-CM version of H35. 212 became effective on October 1, 2023. Patients and methods: This was a retrospective cohort analysis including 137 individuals with dry age-related macular degeneration without sfGA with 5 years of follow. 091 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. ICD-10-CM Range G00-G99. The retina appears to have microcysts, especially in the macula, and the outer retina is thinned. Currently there is no approved or effective treatment. H35. Although there is currently no approved treatment for GA, improved understanding of AMD mechanisms and risk. 292 became effective on October 1, 2023. ICD-10-CM Diagnosis Code R54. Geographic atrophy is a chronic progressive degeneration of the macula and can be seen as part of late-stage age-related macular degeneration (AMD). ICD-10. 89 became effective on October 1, 2023. N42. Both forms of age-related macular degeneration (AMD) are diagnosed by funduscopic examination. 521Atrophy of globe, right eye. Short description: Muscle wasting and atrophy, NEC, unsp site The 2024 edition of ICD-10-CM M62. Background. Parent Code: H47. H44. , dry) or exudative (i. 522 may differ. “Geographic atrophy” is a medical term that refers to later-stage cases of dry age-related macular degeneration (AMD). 293 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. 291 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. family history of atrophic macular degeneration. 2018;125(3):369-390. 3124, H35. ICD-10 code H44. H44. 312 - other international versions of ICD-10 H05. Complement C3 Inhibitor Pegcetacoplan for Geographic Atrophy Secondary to Age-Related Macular Degeneration: A Randomized Phase 2 Trial Ophthalmology . Z90. No abstract available. G00-G99. OMIM. A type 2 excludes note represents "not included here". ICD-10 codes covered if selection criteria are met [covered for ages 65 and above only]: H35. Human genetic data support the complement system as a key component of pathogenesis in AMD, which has been further supported by pre-clinical and recent clinical studies. A Study to Compare the Efficacy and Safety of Intravitreal APL-2 Therapy With Sham Injections in Patients With Geographic Atrophy (GA) Secondary to Age. cutis senilis L90. The definition can be expanded to include extrafoveal lesions that would have an impact on vision if superimposed on the foveal region. ICD-10-CM Diagnosis Code D31. These new blood vessels may then bleed and leak fluid, causing the macula to bulge or lift up from. Request a Demo 14. 019 contain annotation back-referencesAreas of geographic atrophy developed over 2 years in 61% of eyes. 8 years. WALTHAM, Mass. Engl. Fact Checked. 1 - other international versions of ICD-10 H02. “With no treatment options available for patients with geographic atrophy secondary to dry age-related macular degeneration the FDA’s. The Food and Drug Administration (FDA) has accepted for Priority Review the New Drug Application (NDA) for pegcetacoplan for the treatment of geographic atrophy (GA). Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD), characterized by atrophic lesions that first start in the outer retina and progressively expand to cover the macula and the fovea, the center of the macula, leading to irreversible loss of vision over time. At first presentation, more than 30% of incident geographic atrophy (GA) was within the foveal region, and patients with extrafoveal GA developed it within the fovea after approximately 5 years, according to findings published in JAMA Ophthalmology. 6 Pathophysiological studies show that GA often begins in the regions away from the fovea and,. Bacterial vaginitis in pregnancy; Bacterial vaginosis; Bacterial vaginosis in pregnancy. (AMD) identified through ICD-10 codes from 2016 to 2022 was sampled and labeled for the following categories: GA without subfoveal involvement, GA with subfoveal involvement, and no GA. FDA Approves SYFOVRE™ (pegcetacoplan injection) as the First and Only Treatment for Geographic Atrophy (GA), a Leading Cause of Blindness. Sudden-onset of blurring or distortion of vision is often the presenting symptom in the neovascular form. The ReCLAIM-1 Phase I clinical trial was an open-label, single-center trial to evaluate safety and tolerability of elamipretide in 40 subjects with either noncentral geographic atrophy or high-risk drusen without geographic atrophy [38. In the “wet” type of macular degeneration, abnormal blood vessels (known as choroidal neovascularization or CNV) grow under the retina and macula. H02. 019 became effective on October 1, 2023. FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. Geographic Atrophy – The advanced form of non-neovascular AMD, will have one or more zones of well- demarcated retinal pigment epithelial and/or choriocapillaris atrophy. Over time these breaks can expand and stretch and in late stages may resemble the appearance of geographic atrophy similar to that seen in. Geographic atrophy (GA) secondary to age-related macular degeneration (AMD) is characterized by the progressive enlargement of atrophy of the retinal pigment epithelium (RPE) as well as photoreceptor and choriocapillaris loss. 881 MGD, right upper lid. . Advances in imaging. (ICD-10-CM): H35. -) 124 Other disorders of the eye with mcc or thrombolytic agent. Resources to learn about geographic atrophy. The disease eventually progresses to the advanced stage, termed geographic atrophy (GA), wherein large patches of dead RPE and photoreceptors cause irreversible vision loss. The global societal burden of age-related macular degeneration (AMD) is huge due to the disabling vision loss that may ensue. Geographic Atrophy. The result is a “window view” of the choroid and sometimes the sclera. This is the American ICD-10-CM version of H35. Request a Demo 14. Ophthalmology. However, when eyes had 2, 3, or 4 risk factors, the rate of advanced AMD conversion (either large geographic atrophy or neovascularization) increased to 12%, 26%, and 47% respectively. Although the pathogenesis of GA has been studied extensively, there Key messages Studies have identified an increased mortality rate among individuals with geographic atrophy (GA) secondary to age-related macular degeneration. Current murine models fail to fully recapitulate the. A meta-analysis of the global prevalence of any stage of AMD among 129,664 individuals was 8. H35. The underlying choroidal vasculature is more prominent when the pigment epithelium is absent or atrophic. Breaking News – FDA Approves First Geographic Atrophy Treatment, SYFOVRE A groundbreaking, new frontier in macular degeneration treatment has been. H44. The aim of this study was to describe the. Subscribe to Codify by AAPC and get the code details in a flash. The 2024 edition of ICD-10-CM G32. Bailey Freund, MD,3,4 SriniVas Sadda, MD,5,6 Frank G. 362. Because it causes damage (or degeneration) to cells.